SHP-2 Promotes the Maturation of Oligodendrocyte Precursor Cells Through Akt and ERK1/2 Signaling In Vitro

BACKGROUND: Oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes (OLs), which are responsible for myelination. Myelin is essential for saltatory nerve conduction in the vertebrate nervous system. However, the molecular mechanisms of maturation and myelination by oligodendrocyte...

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Detalles Bibliográficos
Autores principales: Liu, Xiujie, Li, Yuanyuan, Zhang, Yong, Lu, Yan, Guo, Wei, Liu, Peng, Zhou, Jiazhen, Xiang, Zhenghua, He, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118803/
https://www.ncbi.nlm.nih.gov/pubmed/21701583
http://dx.doi.org/10.1371/journal.pone.0021058

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