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Exome Sequencing Reveals Comprehensive Genomic Alterations across Eight Cancer Cell Lines
It is well established that genomic alterations play an essential role in oncogenesis, disease progression, and response of tumors to therapeutic intervention. The advances of next-generation sequencing technologies (NGS) provide unprecedented capabilities to scan genomes for changes such as mutatio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118809/ https://www.ncbi.nlm.nih.gov/pubmed/21701589 http://dx.doi.org/10.1371/journal.pone.0021097 |