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Negative enrichment by immunomagnetic nanobeads for unbiased characterization of circulating tumor cells from peripheral blood of cancer patients

BACKGROUND: A limitation of positive selection strategies to enrich for circulating tumor cells (CTCs) is that there might be CTCs with insufficient expression of the surface target marker which may be missed by the procedure. We optimized a method for enrichment, subsequent detection and characteri...

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Detalles Bibliográficos
Autores principales: Liu, Zhian, Fusi, Alberto, Klopocki, Eva, Schmittel, Alexander, Tinhofer, Ingeborg, Nonnenmacher, Anika, Keilholz, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119001/
https://www.ncbi.nlm.nih.gov/pubmed/21595914
http://dx.doi.org/10.1186/1479-5876-9-70