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Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

BACKGROUND: Chronic neurodegeneration comprises an inflammatory response but its contribution to the progression of disease remains unclear. We have previously shown that microglial cells are primed by chronic neurodegeneration, induced by the ME7 strain of prion disease, to synthesize limited pro-i...

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Detalles Bibliográficos
Autores principales:	Murray, Carol L, Skelly, Donal T, Cunningham, Colm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119173/ https://www.ncbi.nlm.nih.gov/pubmed/21586125 http://dx.doi.org/10.1186/1742-2094-8-50

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