Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft

We exploited the dual positive effects of rapamycin to prevent GvHD and control malignant cells upon infusion of unmanipulated grafts from family haploidentical donors to patients affected by advanced hematological malignancies. Preliminary results on 45 patients show the feasibility of this platfor...

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Detalles Bibliográficos
Autores principales: Ciceri, Fabio, Bregni, Marco, Peccatori, Jacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119399/
https://www.ncbi.nlm.nih.gov/pubmed/21716853
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author Ciceri, Fabio
Bregni, Marco
Peccatori, Jacopo
author_facet Ciceri, Fabio
Bregni, Marco
Peccatori, Jacopo
author_sort Ciceri, Fabio
collection PubMed
description We exploited the dual positive effects of rapamycin to prevent GvHD and control malignant cells upon infusion of unmanipulated grafts from family haploidentical donors to patients affected by advanced hematological malignancies. Preliminary results on 45 patients show the feasibility of this platform with an appreciable low rate of GvHD.
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spelling pubmed-31193992011-06-28 Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft Ciceri, Fabio Bregni, Marco Peccatori, Jacopo J Cancer Short Report We exploited the dual positive effects of rapamycin to prevent GvHD and control malignant cells upon infusion of unmanipulated grafts from family haploidentical donors to patients affected by advanced hematological malignancies. Preliminary results on 45 patients show the feasibility of this platform with an appreciable low rate of GvHD. Ivyspring International Publisher 2011-06-03 /pmc/articles/PMC3119399/ /pubmed/21716853 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Short Report
Ciceri, Fabio
Bregni, Marco
Peccatori, Jacopo
Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft
title Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft
title_full Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft
title_fullStr Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft
title_full_unstemmed Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft
title_short Innovative Platforms for Haploidentical Stem Cell Transplantation: The Role of Unmanipulated Donor Graft
title_sort innovative platforms for haploidentical stem cell transplantation: the role of unmanipulated donor graft
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119399/
https://www.ncbi.nlm.nih.gov/pubmed/21716853
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