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Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC)
A variety of therapeutic options are now available for advanced renal cell cancer, including antiangiogenic and anti-mTOR agents. Allogeneic hematopoietic stem cell transplantation, through its graft-versus-tumor effect, can induce clinical responses and prolonged survival in selected cytokine-refra...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119401/ https://www.ncbi.nlm.nih.gov/pubmed/21716855 |
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author | Bregni, Marco Ciceri, Fabio Peccatori, Jacopo |
author_facet | Bregni, Marco Ciceri, Fabio Peccatori, Jacopo |
author_sort | Bregni, Marco |
collection | PubMed |
description | A variety of therapeutic options are now available for advanced renal cell cancer, including antiangiogenic and anti-mTOR agents. Allogeneic hematopoietic stem cell transplantation, through its graft-versus-tumor effect, can induce clinical responses and prolonged survival in selected cytokine-refractory patients. However, the still relevant transplant-related mortality due to toxicity and graft-versus-host disease is an obstacle to its widespread use. |
format | Online Article Text |
id | pubmed-3119401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-31194012011-06-28 Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) Bregni, Marco Ciceri, Fabio Peccatori, Jacopo J Cancer Short Report A variety of therapeutic options are now available for advanced renal cell cancer, including antiangiogenic and anti-mTOR agents. Allogeneic hematopoietic stem cell transplantation, through its graft-versus-tumor effect, can induce clinical responses and prolonged survival in selected cytokine-refractory patients. However, the still relevant transplant-related mortality due to toxicity and graft-versus-host disease is an obstacle to its widespread use. Ivyspring International Publisher 2011-06-05 /pmc/articles/PMC3119401/ /pubmed/21716855 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. |
spellingShingle | Short Report Bregni, Marco Ciceri, Fabio Peccatori, Jacopo Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) |
title | Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) |
title_full | Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) |
title_fullStr | Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) |
title_full_unstemmed | Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) |
title_short | Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC) |
title_sort | allogeneic stem cell transplantation for metastatic renal cell cancer (rcc) |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119401/ https://www.ncbi.nlm.nih.gov/pubmed/21716855 |
work_keys_str_mv | AT bregnimarco allogeneicstemcelltransplantationformetastaticrenalcellcancerrcc AT cicerifabio allogeneicstemcelltransplantationformetastaticrenalcellcancerrcc AT peccatorijacopo allogeneicstemcelltransplantationformetastaticrenalcellcancerrcc |