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Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)

BACKGROUND: Dengue fever is reemerging on the island of Martinique and is a serious threat for the human population. During dengue epidemics, adult Aedes aegypti control with pyrethroid space sprays is implemented in order to rapidly reduce transmission. Unfortunately, vector control programs are fa...

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Autores principales: Marcombe, Sébastien, Darriet, Frédéric, Tolosa, Michel, Agnew, Philip, Duchon, Stéphane, Etienne, Manuel, Yp Tcha, Marie Michèle, Chandre, Fabrice, Corbel, Vincent, Yébakima, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119637/
https://www.ncbi.nlm.nih.gov/pubmed/21713017
http://dx.doi.org/10.1371/journal.pntd.0001202
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author Marcombe, Sébastien
Darriet, Frédéric
Tolosa, Michel
Agnew, Philip
Duchon, Stéphane
Etienne, Manuel
Yp Tcha, Marie Michèle
Chandre, Fabrice
Corbel, Vincent
Yébakima, André
author_facet Marcombe, Sébastien
Darriet, Frédéric
Tolosa, Michel
Agnew, Philip
Duchon, Stéphane
Etienne, Manuel
Yp Tcha, Marie Michèle
Chandre, Fabrice
Corbel, Vincent
Yébakima, André
author_sort Marcombe, Sébastien
collection PubMed
description BACKGROUND: Dengue fever is reemerging on the island of Martinique and is a serious threat for the human population. During dengue epidemics, adult Aedes aegypti control with pyrethroid space sprays is implemented in order to rapidly reduce transmission. Unfortunately, vector control programs are facing operational challenges with the emergence of pyrethroid resistant Ae. aegypti populations. METHODOLOGY/PRINCIPAL FINDINGS: To assess the impact of pyrethroid resistance on the efficacy of treatments, applications of deltamethrin and natural pyrethrins were performed with vehicle-mounted thermal foggers in 9 localities of Martinique, where Ae. aegypti populations are strongly resistant to pyrethroids. Efficacy was assessed by monitoring mortality rates of naturally resistant and laboratory susceptible mosquitoes placed in sentinel cages. Before, during and after spraying, larval and adult densities were estimated. Results showed high mortality rates of susceptible sentinel mosquitoes treated with deltamethrin while resistant mosquitoes exhibited very low mortality. There was no reduction of either larval or adult Ae. aegypti population densities after treatments. CONCLUSIONS/SIGNIFICANCE: This is the first documented evidence that pyrethroid resistance impedes dengue vector control using pyrethroid-based treatments. These results emphasize the need for alternative tools and strategies for dengue control programs.
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spelling pubmed-31196372011-06-27 Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean) Marcombe, Sébastien Darriet, Frédéric Tolosa, Michel Agnew, Philip Duchon, Stéphane Etienne, Manuel Yp Tcha, Marie Michèle Chandre, Fabrice Corbel, Vincent Yébakima, André PLoS Negl Trop Dis Research Article BACKGROUND: Dengue fever is reemerging on the island of Martinique and is a serious threat for the human population. During dengue epidemics, adult Aedes aegypti control with pyrethroid space sprays is implemented in order to rapidly reduce transmission. Unfortunately, vector control programs are facing operational challenges with the emergence of pyrethroid resistant Ae. aegypti populations. METHODOLOGY/PRINCIPAL FINDINGS: To assess the impact of pyrethroid resistance on the efficacy of treatments, applications of deltamethrin and natural pyrethrins were performed with vehicle-mounted thermal foggers in 9 localities of Martinique, where Ae. aegypti populations are strongly resistant to pyrethroids. Efficacy was assessed by monitoring mortality rates of naturally resistant and laboratory susceptible mosquitoes placed in sentinel cages. Before, during and after spraying, larval and adult densities were estimated. Results showed high mortality rates of susceptible sentinel mosquitoes treated with deltamethrin while resistant mosquitoes exhibited very low mortality. There was no reduction of either larval or adult Ae. aegypti population densities after treatments. CONCLUSIONS/SIGNIFICANCE: This is the first documented evidence that pyrethroid resistance impedes dengue vector control using pyrethroid-based treatments. These results emphasize the need for alternative tools and strategies for dengue control programs. Public Library of Science 2011-06-21 /pmc/articles/PMC3119637/ /pubmed/21713017 http://dx.doi.org/10.1371/journal.pntd.0001202 Text en Marcombe et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Marcombe, Sébastien
Darriet, Frédéric
Tolosa, Michel
Agnew, Philip
Duchon, Stéphane
Etienne, Manuel
Yp Tcha, Marie Michèle
Chandre, Fabrice
Corbel, Vincent
Yébakima, André
Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
title Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
title_full Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
title_fullStr Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
title_full_unstemmed Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
title_short Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
title_sort pyrethroid resistance reduces the efficacy of space sprays for dengue control on the island of martinique (caribbean)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119637/
https://www.ncbi.nlm.nih.gov/pubmed/21713017
http://dx.doi.org/10.1371/journal.pntd.0001202
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