The Homeobox Protein CEH-23 Mediates Prolonged Longevity in Response to Impaired Mitochondrial Electron Transport Chain in C. elegans

Recent findings indicate that perturbations of the mitochondrial electron transport chain (METC) can cause extended longevity in evolutionarily diverse organisms. To uncover the molecular basis of how altered METC increases lifespan in C. elegans, we performed an RNAi screen and revealed that three...

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Detalles Bibliográficos
Autores principales: Walter, Ludivine, Baruah, Aiswarya, Chang, Hsin-Wen, Pace, Heather Mae, Lee, Siu Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119657/
https://www.ncbi.nlm.nih.gov/pubmed/21713031
http://dx.doi.org/10.1371/journal.pbio.1001084

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