The Naturally Processed CD95L Elicits a c-Yes/Calcium/PI3K-Driven Cell Migration Pathway

Patients affected by chronic inflammatory disorders display high amounts of soluble CD95L. This homotrimeric ligand arises from the cleavage by metalloproteases of its membrane-bound counterpart, a strong apoptotic inducer. In contrast, the naturally processed CD95L is viewed as an apoptotic antagon...

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Detalles Bibliográficos
Autores principales: Tauzin, Sébastien, Chaigne-Delalande, Benjamin, Selva, Eric, Khadra, Nadine, Daburon, Sophie, Contin-Bordes, Cécile, Blanco, Patrick, Le Seyec, Jacques, Ducret, Thomas, Counillon, Laurent, Moreau, Jean-François, Hofman, Paul, Vacher, Pierre, Legembre, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119658/
https://www.ncbi.nlm.nih.gov/pubmed/21713032
http://dx.doi.org/10.1371/journal.pbio.1001090

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