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Wnt/β-Catenin Signaling Induces the Aging of Mesenchymal Stem Cells through the DNA Damage Response and the p53/p21 Pathway

Recent studies have demonstrated the importance of cellular extrinsic factors in the aging of adult stem cells. However, the effects of an aged cell–extrinsic environment on mesenchymal stem cell (MSC) aging and the factors involved remain unclear. In the current study, we examine the effects of old...

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Detalles Bibliográficos
Autores principales:	Zhang, Da-yong, Wang, Hai-jie, Tan, Yu-zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119703/ https://www.ncbi.nlm.nih.gov/pubmed/21712954 http://dx.doi.org/10.1371/journal.pone.0021397

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