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Reconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activities
The error-free repair of double-strand DNA breaks by homologous recombination (HR) ensures genomic stability using undamaged homologous sequence to copy genetic information. While some of the aspects of the initial steps of HR are understood, the molecular mechanisms underlying events downstream of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119790/ https://www.ncbi.nlm.nih.gov/pubmed/21565563 http://dx.doi.org/10.1016/j.dnarep.2011.03.003 |