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Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering()

Chinese hamster ovary (CHO) cells are the predominant cell factory for the production of recombinant therapeutic proteins. Nevertheless, the lack in publicly available sequence information is severely limiting advances in CHO cell biology, including the exploration of microRNAs (miRNA) as tools for...

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Detalles Bibliográficos
Autores principales: Hackl, Matthias, Jakobi, Tobias, Blom, Jochen, Doppmeier, Daniel, Brinkrolf, Karina, Szczepanowski, Rafael, Bernhart, Stephan H., Siederdissen, Christian Höner zu, Bort, Juan A. Hernandez, Wieser, Matthias, Kunert, Renate, Jeffs, Simon, Hofacker, Ivo L., Goesmann, Alexander, Pühler, Alfred, Borth, Nicole, Grillari, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119918/
https://www.ncbi.nlm.nih.gov/pubmed/21392545
http://dx.doi.org/10.1016/j.jbiotec.2011.02.011