Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking

The increasing number of RNA crystal structures enables a structure-based approach to the discovery of new RNA-binding ligands. To develop the poorly explored area of RNA-ligand docking, we have conducted a virtual screening exercise for a purine riboswitch to probe the strengths and weaknesses of R...

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Detalles Bibliográficos
Autores principales: Daldrop, Peter, Reyes, Francis E., Robinson, David A., Hammond, Colin M., Lilley, David M., Batey, Robert T., Brenk, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119931/
https://www.ncbi.nlm.nih.gov/pubmed/21439477
http://dx.doi.org/10.1016/j.chembiol.2010.12.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119931/
https://www.ncbi.nlm.nih.gov/pubmed/21439477
http://dx.doi.org/10.1016/j.chembiol.2010.12.020

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