Cargando…
Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking
The increasing number of RNA crystal structures enables a structure-based approach to the discovery of new RNA-binding ligands. To develop the poorly explored area of RNA-ligand docking, we have conducted a virtual screening exercise for a purine riboswitch to probe the strengths and weaknesses of R...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119931/ https://www.ncbi.nlm.nih.gov/pubmed/21439477 http://dx.doi.org/10.1016/j.chembiol.2010.12.020 |