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Changes Over Time in Glycemic Control, Insulin Sensitivity, and β-Cell Function in Response to Low-Dose Metformin and Thiazolidinedione Combination Therapy in Patients With Impaired Glucose Tolerance

OBJECTIVE: In the Canadian Normoglycemia Outcome Evaluation (CANOE) trial, low-dose rosiglitazone/metformin reduced the risk of diabetes in subjects with impaired glucose tolerance by 66% over a median of 3.9 years. We evaluate the temporal changes in glycemic control, insulin sensitivity, and β-cel...

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Detalles Bibliográficos
Autores principales:	Retnakaran, Ravi, Qi, Ying, Harris, Stewart B., Hanley, Anthony J., Zinman, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120173/ https://www.ncbi.nlm.nih.gov/pubmed/21709296 http://dx.doi.org/10.2337/dc11-0046

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