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Salsalate Attenuates Free Fatty Acid–Induced Microvascular and Metabolic Insulin Resistance in Humans

OBJECTIVE: Insulin recruits muscle microvasculature, thereby increasing endothelial exchange surface area. Free fatty acids (FFAs) cause insulin resistance by activating inhibitor of κB kinase β. Elevating plasma FFAs impairs insulin’s microvascular and metabolic actions in vivo. Whether salsalate,...

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Detalles Bibliográficos
Autores principales:	Chai, Weidong, Liu, Jia, Jahn, Linda A., Fowler, Dale E., Barrett, Eugene J., Liu, Zhenqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120177/ https://www.ncbi.nlm.nih.gov/pubmed/21617098 http://dx.doi.org/10.2337/dc10-2345

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