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Intravitreal injection of methotrexate in an experimental rabbit model: Determination of pharmacokinetics
PURPOSE: To investigate the pharmacokinetics of intravitreally administered methotrexate. MATERIALS AND METHODS: Twenty-one New Zealand white rabbits were used in the study. The pharmacokinetics of intravitreally injected 800 μg/0.1 ml of methotrexate was investigated. Intravitreal concentration of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120238/ https://www.ncbi.nlm.nih.gov/pubmed/21586839 http://dx.doi.org/10.4103/0301-4738.81026 |