Cargando…
Intravitreal injection of methotrexate in an experimental rabbit model: Determination of pharmacokinetics
PURPOSE: To investigate the pharmacokinetics of intravitreally administered methotrexate. MATERIALS AND METHODS: Twenty-one New Zealand white rabbits were used in the study. The pharmacokinetics of intravitreally injected 800 μg/0.1 ml of methotrexate was investigated. Intravitreal concentration of...
Autores principales: | Ozkan, Ebru Bener, Ozcan, Altan A, Alparslan, Nazan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120238/ https://www.ncbi.nlm.nih.gov/pubmed/21586839 http://dx.doi.org/10.4103/0301-4738.81026 |
Ejemplares similares
-
Intravitreal injection of methotrexate in an experimental rabbit model: Determination of ultrastructural changes
por: Ozkan, Ebru B, et al.
Publicado: (2013) -
Pharmacokinetics and tolerance study of intravitreal injection of dexamethasone-loaded nanoparticles in rabbits
por: Zhang, Linhua, et al.
Publicado: (2009) -
Pharmacokinetics of intravitreal bevacizumab (Avastin(®)) in rabbits
por: Sinapis, Christos I, et al.
Publicado: (2011) -
Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits
por: Damico, Francisco Max, et al.
Publicado: (2012) -
Intraocular Pharmacokinetics of 10-fold Intravitreal Ranibizumab Injection Dose in Rabbits
por: Kim, Hyeong Min, et al.
Publicado: (2020)