Neoline from Aconitum flavum Hand

The title compound, C(24)H(39)NO(6) [systematic name: (1α,6α,14α,16β)-N-ethyl-6,16-dimeth­oxy-4-meth­oxy­methylaconitane-1,8,14-triol], is a C(19)-diterpenoid alkaloid from the roots of Aconitum flavum Hand. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-mem...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Gou, Xiong-Jun, Song, Qin, Chen, Feng-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120301/
https://www.ncbi.nlm.nih.gov/pubmed/21754813
http://dx.doi.org/10.1107/S1600536811015170
Descripción
Sumario:The title compound, C(24)H(39)NO(6) [systematic name: (1α,6α,14α,16β)-N-ethyl-6,16-dimeth­oxy-4-meth­oxy­methylaconitane-1,8,14-triol], is a C(19)-diterpenoid alkaloid from the roots of Aconitum flavum Hand. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings. Both five-membered rings adopt envelope conformations. Two six-membered rings adopt chair conformations, whereas the other two adopt boat conformations. Intra­molecular O—H⋯O and O—H⋯N and inter­molecular O—H⋯O hydrogen bonds are present in the structure. In the crystal, one methyl group is disordered over two sites with an occupancy ratio of 0.70 (3):0.30 (3).

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