Neoline from Aconitum flavum Hand

The title compound, C(24)H(39)NO(6) [systematic name: (1α,6α,14α,16β)-N-ethyl-6,16-dimeth­oxy-4-meth­oxy­methylaconitane-1,8,14-triol], is a C(19)-diterpenoid alkaloid from the roots of Aconitum flavum Hand. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-mem...

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Autores principales: Liu, Wei, Gou, Xiong-Jun, Song, Qin, Chen, Feng-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120301/
https://www.ncbi.nlm.nih.gov/pubmed/21754813
http://dx.doi.org/10.1107/S1600536811015170
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author Liu, Wei
Gou, Xiong-Jun
Song, Qin
Chen, Feng-Zheng
author_facet Liu, Wei
Gou, Xiong-Jun
Song, Qin
Chen, Feng-Zheng
author_sort Liu, Wei
collection PubMed
description The title compound, C(24)H(39)NO(6) [systematic name: (1α,6α,14α,16β)-N-ethyl-6,16-dimeth­oxy-4-meth­oxy­methylaconitane-1,8,14-triol], is a C(19)-diterpenoid alkaloid from the roots of Aconitum flavum Hand. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings. Both five-membered rings adopt envelope conformations. Two six-membered rings adopt chair conformations, whereas the other two adopt boat conformations. Intra­molecular O—H⋯O and O—H⋯N and inter­molecular O—H⋯O hydrogen bonds are present in the structure. In the crystal, one methyl group is disordered over two sites with an occupancy ratio of 0.70 (3):0.30 (3).
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spelling pubmed-31203012011-07-13 Neoline from Aconitum flavum Hand Liu, Wei Gou, Xiong-Jun Song, Qin Chen, Feng-Zheng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(24)H(39)NO(6) [systematic name: (1α,6α,14α,16β)-N-ethyl-6,16-dimeth­oxy-4-meth­oxy­methylaconitane-1,8,14-triol], is a C(19)-diterpenoid alkaloid from the roots of Aconitum flavum Hand. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings. Both five-membered rings adopt envelope conformations. Two six-membered rings adopt chair conformations, whereas the other two adopt boat conformations. Intra­molecular O—H⋯O and O—H⋯N and inter­molecular O—H⋯O hydrogen bonds are present in the structure. In the crystal, one methyl group is disordered over two sites with an occupancy ratio of 0.70 (3):0.30 (3). International Union of Crystallography 2011-05-20 /pmc/articles/PMC3120301/ /pubmed/21754813 http://dx.doi.org/10.1107/S1600536811015170 Text en © Liu et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Liu, Wei
Gou, Xiong-Jun
Song, Qin
Chen, Feng-Zheng
Neoline from Aconitum flavum Hand
title Neoline from Aconitum flavum Hand
title_full Neoline from Aconitum flavum Hand
title_fullStr Neoline from Aconitum flavum Hand
title_full_unstemmed Neoline from Aconitum flavum Hand
title_short Neoline from Aconitum flavum Hand
title_sort neoline from aconitum flavum hand
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120301/
https://www.ncbi.nlm.nih.gov/pubmed/21754813
http://dx.doi.org/10.1107/S1600536811015170
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AT chenfengzheng neolinefromaconitumflavumhand

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