Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate

In the isoquinoline ring system of the title mol­ecule, C(22)H(20)N(2)O(5), the N-heterocyclic ring is in a half-boat conformation. The least-squares plane of the dioxa-2-aza­spiro ring [maximum deviation = 0.076 (1) Å] and forms a dihedral angle of 14.54 (4)° with the phenyl ring. In the crystal, m...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Quah, Ching Kheng, Huang, Chengmei, Yu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120312/
https://www.ncbi.nlm.nih.gov/pubmed/21754882
http://dx.doi.org/10.1107/S160053681101899X
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author Fun, Hoong-Kun
Quah, Ching Kheng
Huang, Chengmei
Yu, Haitao
author_facet Fun, Hoong-Kun
Quah, Ching Kheng
Huang, Chengmei
Yu, Haitao
author_sort Fun, Hoong-Kun
collection PubMed
description In the isoquinoline ring system of the title mol­ecule, C(22)H(20)N(2)O(5), the N-heterocyclic ring is in a half-boat conformation. The least-squares plane of the dioxa-2-aza­spiro ring [maximum deviation = 0.076 (1) Å] and forms a dihedral angle of 14.54 (4)° with the phenyl ring. In the crystal, mol­ecules are linked via inter­molecular C—H⋯O hydrogen bonds into layers parallel to (100).
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spelling pubmed-31203122011-07-13 Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate Fun, Hoong-Kun Quah, Ching Kheng Huang, Chengmei Yu, Haitao Acta Crystallogr Sect E Struct Rep Online Organic Papers In the isoquinoline ring system of the title mol­ecule, C(22)H(20)N(2)O(5), the N-heterocyclic ring is in a half-boat conformation. The least-squares plane of the dioxa-2-aza­spiro ring [maximum deviation = 0.076 (1) Å] and forms a dihedral angle of 14.54 (4)° with the phenyl ring. In the crystal, mol­ecules are linked via inter­molecular C—H⋯O hydrogen bonds into layers parallel to (100). International Union of Crystallography 2011-05-25 /pmc/articles/PMC3120312/ /pubmed/21754882 http://dx.doi.org/10.1107/S160053681101899X Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Quah, Ching Kheng
Huang, Chengmei
Yu, Haitao
Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
title Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
title_full Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
title_fullStr Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
title_full_unstemmed Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
title_short Methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
title_sort methyl 4′-benzyl-2,2′-dimethyl-1,3-dioxo-2,3-dihydro-1h,4′h-spiro­[iso­quinoline-4,5′-oxazole]-4′-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120312/
https://www.ncbi.nlm.nih.gov/pubmed/21754882
http://dx.doi.org/10.1107/S160053681101899X
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AT huangchengmei methyl4benzyl22dimethyl13dioxo23dihydro1h4hspiroisoquinoline45oxazole4carboxylate
AT yuhaitao methyl4benzyl22dimethyl13dioxo23dihydro1h4hspiroisoquinoline45oxazole4carboxylate

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