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The title compound {systematic name: N-cyclo­hexyl­carba­moyl-4-[2-(7-meth­oxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-2-yl)eth­yl]benzene­sulfonamide}, C(27)H(33)N(3)O(6)S, displays an intra­molecular N—H⋯O=S inter­action, as well as inter­molecular N—H⋯O=C hydrogen bonds. The latter...

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Detalles Bibliográficos
Autores principales: Gelbrich, Thomas, Haddow, Mairi F., Griesser, Ulrich J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120417/
https://www.ncbi.nlm.nih.gov/pubmed/21754738
http://dx.doi.org/10.1107/S1600536811016680
Descripción
Sumario:The title compound {systematic name: N-cyclo­hexyl­carba­moyl-4-[2-(7-meth­oxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-2-yl)eth­yl]benzene­sulfonamide}, C(27)H(33)N(3)O(6)S, displays an intra­molecular N—H⋯O=S inter­action, as well as inter­molecular N—H⋯O=C hydrogen bonds. The latter inter­actions lead to the formation of hydrogen-bonded chains parallel to the c axis. The conformation of the sulfonyl­urea fragment is in agreement with a recent theoretical study [Kasetti et al. (2010 ▶). J. Phys. Chem. B, 114, 11603–11610].

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