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2,4-Bis(2-eth­oxy­phen­yl)-7-methyl-3-aza­bicyclo­[3.3.1]nonan-9-one

The crystal structure of the title compound, C(25)H(31)NO(3), exists in a twin-chair conformation with an equatorial orientation of the ortho-eth­oxy­phenyl groups. According to Cremer and Pople [Cremer & Pople (1975 ▶), J. Am. Chem. Soc. 97, 1354–1358], both the piperidone and cyclo­hexa­none r...

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Detalles Bibliográficos
Autores principales: Parthiban, P., Ramkumar, V., Park, Dong Ho, Jeong, Yeon Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120546/
https://www.ncbi.nlm.nih.gov/pubmed/21754845
http://dx.doi.org/10.1107/S1600536811018472
Descripción
Sumario:The crystal structure of the title compound, C(25)H(31)NO(3), exists in a twin-chair conformation with an equatorial orientation of the ortho-eth­oxy­phenyl groups. According to Cremer and Pople [Cremer & Pople (1975 ▶), J. Am. Chem. Soc. 97, 1354–1358], both the piperidone and cyclo­hexa­none rings are significantly puckered with total puckering amplitutdes Q (T) of 0.5889 (18) and 0.554 (2) Å, respectively. The ortho-eth­oxy­phenyl groups are located on either side of the secondary amino group and make a dihedral angle of 12.41 (4)° with respect to each other. The methyl group on the cyclo­hexa­none part occupies an exocyclic equatorial disposition. The crystal packing is stabilized by weak van der Waals inter­actions.