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Therapeutic potential of N-acetylcysteine as an antiplatelet agent in patients with type-2 diabetes

BACKGROUND: Platelet hyperaggregability is a pro-thrombotic feature of type-2 diabetes, associated with low levels of the antioxidant glutathione (GSH). Clinical delivery of N-acetylcysteine (NAC), a biosynthetic precursor of GSH, may help redress a GSH shortfall in platelets, thereby reducing throm...

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Detalles Bibliográficos
Autores principales:	Gibson, Kyle R, Winterburn, Tim J, Barrett, Fiona, Sharma, Sushma, MacRury, Sandra M, Megson, Ian L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120650/ https://www.ncbi.nlm.nih.gov/pubmed/21600014 http://dx.doi.org/10.1186/1475-2840-10-43

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