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CD39(+ )Regulatory T cells suppress generation and differentiation of Th17 cells in human malignant pleural effusion via a LAP-dependent mechanism

BACKGROUND: Both regulatory T cells (Tregs) and T helper IL-17-producing cells (Th17 cells) have been found to be involved in human malignancies, however, the possible implication of Tregs in regulating generation and differentiation of Th17 cells in malignant pleural effusion remains to be elucidat...

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Detalles Bibliográficos
Autores principales: Ye, Zhi-Jian, Zhou, Qiong, Zhang, Jian-Chu, Li, Xiao, Wu, Cong, Qin, Shou-Ming, Xin, Jian-Bao, Shi, Huan-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120670/
https://www.ncbi.nlm.nih.gov/pubmed/21663645
http://dx.doi.org/10.1186/1465-9921-12-77

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