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A dual role for microglia in promoting tissue inhibitor of metalloproteinase (TIMP) expression in glial cells in response to neuroinflammatory stimuli

BACKGROUND: By neutralizing the effect of the matrix metalloproteinases (MMPs), the tissue inhibitors of matrix metalloproteinases (TIMPs) play a critical role in maintaining tissue proteolysis in balance. As the major reactive glial cell types in the central nervous system (CNS), microglia and astr...

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Detalles Bibliográficos
Autores principales: Welser-Alves, Jennifer V, Crocker, Stephen J, Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120696/
https://www.ncbi.nlm.nih.gov/pubmed/21631912
http://dx.doi.org/10.1186/1742-2094-8-61