Cargando…
Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker
Autism is a neurodevelopmental disorder characterized by deficits in verbal communication, social interactions, and the presence of repetitive, stereotyped and compulsive behaviors. Excessive early brain growth is found commonly in some patients and may contribute to disease phenotype. Reports of in...
Autores principales: | Ray, Balmiki, Long, Justin M., Sokol, Deborah K., Lahiri, Debomoy K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120811/ https://www.ncbi.nlm.nih.gov/pubmed/21731612 http://dx.doi.org/10.1371/journal.pone.0020405 |
Ejemplares similares
-
Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway
por: Lahiri, Debomoy K., et al.
Publicado: (2013) -
Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue
por: Ray, Balmiki, et al.
Publicado: (2016) -
Rivastigmine Lowers Aβ and Increases sAPPα Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons
por: Bailey, Jason A., et al.
Publicado: (2011) -
APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder
por: Sokol, Deborah K., et al.
Publicado: (2023) -
Secreted Amyloid Precursor Protein Alpha (sAPPα Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes
por: Peppercorn, Katie, et al.
Publicado: (2023)