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DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

Hyperphosphorylation of RPA2 at serine 4 and serine 8 (S4, S8) has been used as a marker for activation of the DNA damage response. What types of DNA lesions cause RPA2 hyperphosphorylation, which kinase(s) are responsible for them, and what is the biological outcome of these phosphorylations, howev...

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Detalles Bibliográficos
Autores principales:	Liaw, Hungjiun, Lee, Deokjae, Myung, Kyungjae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120867/ https://www.ncbi.nlm.nih.gov/pubmed/21731742 http://dx.doi.org/10.1371/journal.pone.0021424

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