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Two-stage flux balance analysis of metabolic networks for drug target identification
BACKGROUND: Efficient identification of drug targets is one of major challenges for drug discovery and drug development. Traditional approaches to drug target identification include literature search-based target prioritization and in vitro binding assays which are both time-consuming and labor inte...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121111/ https://www.ncbi.nlm.nih.gov/pubmed/21689470 http://dx.doi.org/10.1186/1752-0509-5-S1-S11 |