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Two-stage flux balance analysis of metabolic networks for drug target identification

BACKGROUND: Efficient identification of drug targets is one of major challenges for drug discovery and drug development. Traditional approaches to drug target identification include literature search-based target prioritization and in vitro binding assays which are both time-consuming and labor inte...

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Detalles Bibliográficos
Autores principales: Li, Zhenping, Wang, Rui-Sheng, Zhang, Xiang-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121111/
https://www.ncbi.nlm.nih.gov/pubmed/21689470
http://dx.doi.org/10.1186/1752-0509-5-S1-S11

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