A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

We describe a protocol for the rapid and sensitive quantification of disease severity in mouse models of cerebella ataxia. It is derived from previously published phenotype assessments in several disease models, including spinocerebellar ataxias, Huntington s disease and spinobulbar muscular atrophy...

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Detalles Bibliográficos
Autores principales: Guyenet, Stephan J., Furrer, Stephanie A., Damian, Vincent M., Baughan, Travis D., La Spada, Albert R., Garden, Gwenn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2010
Materias:
JoVE Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121238/
https://www.ncbi.nlm.nih.gov/pubmed/20495529
http://dx.doi.org/10.3791/1787

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