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Impaired Insulin Secretion and Enhanced Insulin Sensitivity in Cholecystokinin-Deficient Mice

OBJECTIVE: Cholecystokinin (CCK) is released in response to lipid intake and stimulates insulin secretion. We hypothesized that CCK deficiency would alter the regulation of insulin secretion and glucose homeostasis. RESEARCH DESIGN AND METHODS: We used quantitative magnetic resonance imaging to dete...

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Detalles Bibliográficos
Autores principales: Lo, Chun-Min, Obici, Silvana, Dong, H. Henry, Haas, Michael, Lou, Dawnwen, Kim, Dae Hyun, Liu, Min, D’Alessio, David, Woods, Stephen C., Tso, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121422/
https://www.ncbi.nlm.nih.gov/pubmed/21602512
http://dx.doi.org/10.2337/db10-0789