Suppression of FoxO1 Activity by Long-Chain Fatty Acyl Analogs

OBJECTIVE: Overactivity of the Forkhead transcription factor FoxO1 promotes diabetic hyperglycemia, dyslipidemia, and acute-phase response, whereas suppression of FoxO1 activity by insulin may alleviate diabetes. The reported efficacy of long-chain fatty acyl (LCFA) analogs of the MEDICA series in a...

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Detalles Bibliográficos
Autores principales: Zatara, Ghadeer, Hertz, Rachel, Shaked, Maayan, Mayorek, Nina, Morad, Etedal, Grad, Etty, Cahan, Amos, Danenberg, Haim D., Unterman, Terry G., Bar-Tana, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121436/
https://www.ncbi.nlm.nih.gov/pubmed/21602511
http://dx.doi.org/10.2337/db11-0248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121436/
https://www.ncbi.nlm.nih.gov/pubmed/21602511
http://dx.doi.org/10.2337/db11-0248

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