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Thrombospondin-1: An Islet Endothelial Cell Signal of Importance for β-Cell Function

OBJECTIVE: Loss of thrombospondin (TSP)-1 in pancreatic islets has been shown to cause islet hyperplasia. This study tested the hypothesis that endothelial-derived TSP-1 is important for β-cell function. RESEARCH DESIGN AND METHODS: Islet function was evaluated both in vivo and in vitro. Messenger R...

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Detalles Bibliográficos
Autores principales:	Olerud, Johan, Mokhtari, Dariush, Johansson, Magnus, Christoffersson, Gustaf, Lawler, Jack, Welsh, Nils, Carlsson, Per-Ola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121439/ https://www.ncbi.nlm.nih.gov/pubmed/21617177 http://dx.doi.org/10.2337/db10-0277

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