Genetic Defect in Phospholipase Cδ1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis

OBJECTIVE: Regulation of obesity development is an important issue to prevent metabolic syndromes. Gene-disrupted mice of phospholipase Cδ1 (PLCδ1), a key enzyme of phosphoinositide turnover, seemed to show leanness. Here we examined whether and how PLCδ1 is involved in obesity. RESEARCH DESIGN AND...

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Detalles Bibliográficos
Autores principales: Hirata, Masayuki, Suzuki, Mutsumi, Ishii, Rika, Satow, Reiko, Uchida, Takafumi, Kitazumi, Tomoya, Sasaki, Tsutomu, Kitamura, Tadahiro, Yamaguchi, Hideki, Nakamura, Yoshikazu, Fukami, Kiyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121440/
https://www.ncbi.nlm.nih.gov/pubmed/21617180
http://dx.doi.org/10.2337/db10-1500

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