Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

OBJECTIVE: Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through different signaling pathways. The nuclear BA receptor farnesoid X receptor (FXR) regulates pathways in BA, lipid, glucose, and energy metabolism, which become dysregulated in obesity. However, the role...

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Detalles Bibliográficos
Autores principales: Prawitt, Janne, Abdelkarim, Mouaadh, Stroeve, Johanna H.M., Popescu, Iuliana, Duez, Helene, Velagapudi, Vidya R., Dumont, Julie, Bouchaert, Emmanuel, van Dijk, Theo H., Lucas, Anthony, Dorchies, Emilie, Daoudi, Mehdi, Lestavel, Sophie, Gonzalez, Frank J., Oresic, Matej, Cariou, Bertrand, Kuipers, Folkert, Caron, Sandrine, Staels, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121443/
https://www.ncbi.nlm.nih.gov/pubmed/21593203
http://dx.doi.org/10.2337/db11-0030

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