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Suppressing glucose uptake and acetic acid production increases membrane protein overexpression in Escherichia coli
BACKGROUND: The production of integral membrane spanning proteins (IMP's) constitutes a bottleneck in pharmaceutical development. It was long considered that the state-of-the-art was to produce the proteins as inclusion bodies using a powerful induction system. However, the quality of the prote...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121589/ https://www.ncbi.nlm.nih.gov/pubmed/21586123 http://dx.doi.org/10.1186/1475-2859-10-35 |