α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

BACKGROUND: The mangosteen fruit has a long history of medicinal use in Chinese and Ayurvedic medicine. Recently, the compound α-mangostin, which is isolated from the pericarp of the fruit, was shown to induce cell death in various types of cancer cells in in vitro studies. This led us to investigat...

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Detalles Bibliográficos
Autores principales: Shibata, Masa-Aki, Iinuma, Munekazu, Morimoto, Junji, Kurose, Hitomi, Akamatsu, Kanako, Okuno, Yasushi, Akao, Yukihiro, Otsuki, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121600/
https://www.ncbi.nlm.nih.gov/pubmed/21639868
http://dx.doi.org/10.1186/1741-7015-9-69

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