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Quality of tumor lysates used for pulsing dendritic cells is influenced by the method used to harvest adherent tumor cells

BACKGROUND: Lysates from tumor cells are reported to induce maturation of dendritic cells (DCs) and are used in clinical settings for DC-based vaccination against solid tumors. Nevertheless, the maturation inducing effect of tumor lysates on DCs is discussed controversially and the efficacy of tumor...

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Detalles Bibliográficos
Autores principales: Herzog, Gloria Isabelle, Solgi, Ghasem, Wiegmann, Denis S, Nienhaus, Christian, Schrezenmeier, Hubert, Yildiz, Tatjana, Lotfi, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121621/
https://www.ncbi.nlm.nih.gov/pubmed/21615909
http://dx.doi.org/10.1186/1756-0500-4-153