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StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase
BACKGROUND: Most of the currently used methods for protein function prediction rely on sequence-based comparisons between a query protein and those for which a functional annotation is provided. A serious limitation of sequence similarity-based approaches for identifying residue conservation among p...
Autores principales: | Zemla, Adam T, Lang, Dorothy M, Kostova, Tanya, Andino, Raul, Ecale Zhou, Carol L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121648/ https://www.ncbi.nlm.nih.gov/pubmed/21635786 http://dx.doi.org/10.1186/1471-2105-12-226 |
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