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Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells

BACKGROUND: Castration-resistance in prostate cancer (PC) is a critical event hallmarking a switch to a more aggressive phenotype. Neuroendocrine differentiation and upregulation of NFκB transcriptional activity are two mechanisms that have been independently linked to this process. METHODS: We inve...

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Detalles Bibliográficos
Autores principales: Patrikidou, Anna, Vlachostergios, Panagiotis J, Voutsadakis, Ioannis A, Hatzidaki, Eleana, Valeri, Rosalia-Maria, Destouni, Chariklia, Apostolou, Effie, Daliani, Danai, Papandreou, Christos N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121665/
https://www.ncbi.nlm.nih.gov/pubmed/21569620
http://dx.doi.org/10.1186/1475-2867-11-13