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Malignant catatonia due to anti-NMDA-receptor encephalitis in a 17-year-old girl: case report

Anti-NMDA-Receptor encephalitis is a severe form of encephalitis that was recently identified in the context of acute neuropsychiatric presentation. Here, we describe the case of a 17-year-old girl referred for an acute mania with psychotic features and a clinical picture deteriorated to a catatonic...

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Detalles Bibliográficos
Autores principales: Consoli, Angèle, Ronen, Karine, An-Gourfinkel, Isabelle, Barbeau, Martine, Marra, Donata, Costedoat-Chalumeau, Nathalie, Montefiore, Delphine, Maksud, Philippe, Bonnot, Olivier, Didelot, Adrien, Amoura, Zahir, Vidailhet, Marie, Cohen, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121673/
https://www.ncbi.nlm.nih.gov/pubmed/21569502
http://dx.doi.org/10.1186/1753-2000-5-15
Descripción
Sumario:Anti-NMDA-Receptor encephalitis is a severe form of encephalitis that was recently identified in the context of acute neuropsychiatric presentation. Here, we describe the case of a 17-year-old girl referred for an acute mania with psychotic features and a clinical picture deteriorated to a catatonic state. Positive diagnosis of anti-NMDA-receptor encephalitis suggested specific treatment. She improved after plasma exchange and immunosuppressive therapy. Post-cognitive sequelae (memory impairment) disappeared within 2-year follow-up and intensive cognitive rehabilitation.