Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation

BACKGROUND: Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resistance and glucose intolerance in PCOS patients, and their...

Descripción completa

Detalles Bibliográficos
Autores principales: Sabatini, Mary E, Guo, Lankai, Lynch, Maureen P, Doyle, Joseph O, Lee, HoJoon, Rueda, Bo R, Styer, Aaron K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121715/
https://www.ncbi.nlm.nih.gov/pubmed/21605417
http://dx.doi.org/10.1186/1757-2215-4-8

Ejemplares similares

Ejemplares similares