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Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis
IRF8 (Interferon Regulatory Factor 8) plays an important role in defenses against intracellular pathogens, including several aspects of myeloid cells function. It is required for ontogeny and maturation of macrophages and dendritic cells, for activation of anti-microbial defenses, and for production...
Autores principales: | Marquis, Jean-François, Kapoustina, Oxana, Langlais, David, Ruddy, Rebecca, Dufour, Catherine Rosa, Kim, Bae-Hoon, MacMicking, John D., Giguère, Vincent, Gros, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121741/ https://www.ncbi.nlm.nih.gov/pubmed/21731497 http://dx.doi.org/10.1371/journal.pgen.1002097 |
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