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Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis

IRF8 (Interferon Regulatory Factor 8) plays an important role in defenses against intracellular pathogens, including several aspects of myeloid cells function. It is required for ontogeny and maturation of macrophages and dendritic cells, for activation of anti-microbial defenses, and for production...

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Detalles Bibliográficos
Autores principales: Marquis, Jean-François, Kapoustina, Oxana, Langlais, David, Ruddy, Rebecca, Dufour, Catherine Rosa, Kim, Bae-Hoon, MacMicking, John D., Giguère, Vincent, Gros, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121741/
https://www.ncbi.nlm.nih.gov/pubmed/21731497
http://dx.doi.org/10.1371/journal.pgen.1002097

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