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Pharmacological Characterization of [(3)H]CHIBA-3007 Binding to Glycine Transporter 1 in the Rat Brain
Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist at the N-methyl-D-aspartate (NMDA) receptors in the brain. In the present study, we developed a novel radioligand, [(3)H]3-chloro-N-((S)-((R)-1-methylpiperidin-2-yl)(thioph...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121759/ https://www.ncbi.nlm.nih.gov/pubmed/21731704 http://dx.doi.org/10.1371/journal.pone.0021322 |