Extracellular Matrix Dynamics in Hepatocarcinogenesis: a Comparative Proteomics Study of PDGFC Transgenic and Pten Null Mouse Models

We are reporting qualitative and quantitative changes of the extracellular matrix (ECM) and associated receptor proteomes, occurring during the transition from liver fibrosis and steatohepatitis to hepatocellular carcinoma (HCC). We compared two mouse models relevant to human HCC: PDGFC transgenic (...

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Detalles Bibliográficos
Autores principales: Lai, Keane K. Y., Shang, Sufen, Lohia, Neha, Booth, Garrett C., Masse, Derek J., Fausto, Nelson, Campbell, Jean S., Beretta, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121762/
https://www.ncbi.nlm.nih.gov/pubmed/21731504
http://dx.doi.org/10.1371/journal.pgen.1002147

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