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DNA Methylation Changes in Atypical Adenomatous Hyperplasia, Adenocarcinoma In Situ, and Lung Adenocarcinoma

BACKGROUND: Aberrant DNA methylation is common in lung adenocarcinoma, but its timing in the phases of tumor development is largely unknown. Delineating when abnormal DNA methylation arises may provide insight into the natural history of lung adenocarcinoma and the role that DNA methylation alterati...

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Detalles Bibliográficos
Autores principales: Selamat, Suhaida A., Galler, Janice S., Joshi, Amit D., Fyfe, M. Nicky, Campan, Mihaela, Siegmund, Kimberly D., Kerr, Keith M., Laird-Offringa, Ite A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121768/
https://www.ncbi.nlm.nih.gov/pubmed/21731750
http://dx.doi.org/10.1371/journal.pone.0021443