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A siRNA-Based Screen for Genes Involved in Chromosome End Protection
Telomeres are nucleoprotein complexes which protect the ends of linear chromosomes from detection as DNA damage and provide a sequence buffer against replication-associated shortening. In mammals, telomeres consist of repetitive DNA sequence (TTAGGG) and associated proteins. The telomeric core compl...
Autores principales: | Lackner, Daniel H., Durocher, Daniel, Karlseder, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121770/ https://www.ncbi.nlm.nih.gov/pubmed/21760879 http://dx.doi.org/10.1371/journal.pone.0021407 |
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