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IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease
To through light on the mechanisms underlying the stimulation and persistence of glial cell activation in Parkinsonism, we investigate the function of IFN-γ and TNF-α in experimental models of Parkinson's disease and analyze their relation with local glial cell activation. It was found that IFN...
Autores principales: | Barcia, C, Ros, C M, Annese, V, Gómez, A, Ros-Bernal, F, Aguado-Yera, D, Martínez-Pagán, M E, de Pablos, V, Fernandez-Villalba, E, Herrero, M T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122054/ https://www.ncbi.nlm.nih.gov/pubmed/21472005 http://dx.doi.org/10.1038/cddis.2011.17 |
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