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Germline Fitness-Based Scoring of Cancer Mutations
A key goal in cancer research is to find the genomic alterations that underlie malignant cells. Genomics has proved successful in identifying somatic variants at a large scale. However, it has become evident that a typical cancer exhibits a heterogenous mutation pattern across samples. Cases where t...
Autores principales: | Fischer, Andrej, Greenman, Chris, Mustonen, Ville |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122307/ https://www.ncbi.nlm.nih.gov/pubmed/21441214 http://dx.doi.org/10.1534/genetics.111.127480 |
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