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Germline Fitness-Based Scoring of Cancer Mutations

A key goal in cancer research is to find the genomic alterations that underlie malignant cells. Genomics has proved successful in identifying somatic variants at a large scale. However, it has become evident that a typical cancer exhibits a heterogenous mutation pattern across samples. Cases where t...

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Detalles Bibliográficos
Autores principales: Fischer, Andrej, Greenman, Chris, Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122307/
https://www.ncbi.nlm.nih.gov/pubmed/21441214
http://dx.doi.org/10.1534/genetics.111.127480

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